Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732924 | 1.00 | LMNA (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL2615557 | 1.00 | LMNA (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL27927629 | 0.98 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL12750110 | 0.87 | LMNA (0.48) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL20997773 | 0.82 | LMNA (0.59) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL27622870 | 0.81 | L3MBTL1 (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL14480099 | 0.79 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL11209565 | 0.79 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL8220014 | 0.79 | LMNA (0.42) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL11209562 | 0.79 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101985424-B | Method for synthesizing o-nitroacetophenone compound | UNIV ZHEJIANG TECHNOLOGY | 2013-05-29 | — | — | CN | claimed |
| US-20120077941-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| CN-101985424-A | Method for synthesizing o-nitroacetophenone compound | UNIV ZHEJIANG TECHNOLOGY | 2011-03-16 | — | — | CN | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| CN-1187756-A | Crop protection compositions | CIBA GEIGY AG (CH) | 1998-07-15 | — | — | CN | claimed |
| CN-114685393-A | Novel oxime derivative, preparation method thereof and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2022-07-01 | — | — | CN | disclosed |
| EP-3227018-B1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | UNIV VIRGINIA COMMONWEALTH (US) | 2021-06-30 | — | — | EP | disclosed |
| CN-107739322-B | Synthetic method of sulfonamide compound | 济南大学 | 2020-06-23 | — | — | CN | disclosed |
| US-10000453-B2 | Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20170362181-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | VIRGINIA COMMONWEALTH UNIVERSITY | 2017-12-21 | — | — | US | disclosed |
| EP-3227018-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | Virginia Commonwealth University (US) | 2017-10-11 | — | — | EP | disclosed |
| US-9656256-B2 | N-heterocyclic carbene type palladium catalyst and its preparation method as well as applications | SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2017-05-23 | — | — | US | disclosed |
| US-5231227-A | Optically active hydroxybenzylamine derivative and process for producing said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0311385-B1 | OPTICALLY ACTIVE HYDROXYBENZYLAMINE DERIVATIVE, OPTICALLY ACTIVE AMINE-BORON COMPOUND CONTAINING SAID DERIVATIVE, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND BY USING SAID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5120853-A | Reacting optically active amine-boron complex with oxime or ketone to produce opotically active amine or alcohol compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-09 | — | — | US | disclosed |
| CN-1052665-A | The pyridinyl carbamates compound, and preparation method thereof and the Biocidal composition that is used to prevent and treat harmful organisms that contains them | ISHIHARA SANGYO KAISHA (JP) | 1991-07-03 | — | — | CN | disclosed |
| US-5011989-A | Asymmetric reducing agents | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-30 | — | — | US | disclosed |
| CN-1036879-A | BIOCIDE COMPOSITIONS | ISHIHARA SANGYO KAISHA (JP) | 1989-11-08 | — | — | CN | disclosed |
| EP-0311385-A2 | Optically active hydroxybenzylamine derivative, optically active amine-boron compound containing said derivative, and process for producing optically active compound by using said compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362181-A1 | CHELATION DIRECTED C-H ACTIVATION REACTIONS CATALYZED BY SOLID-SUPPORTED PALLADIUM(II) CATALYSTS | WASF2, SCO2, SOD1 | LMNA 3565/4885L3MBTL1 1181/4885MAPK1 1610/4885 |
| US-10000453-B2 | Chelation directed C—H activation reactions catalyzed by solid-supported palladium(II) catalysts | WASF2, SOD1, CD274 | LMNA 3454/4885L3MBTL1 1229/4885MAPK1 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.