Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503299 | 0.84 | TAAR1 (0.55) | ALDH1A1MAOBCYP3A4 | |
| SCHEMBL10871647 | 0.81 | TSHR (0.50) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL9118677 | 0.81 | TLR4 (0.42) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9292349 | 0.79 | TSHR (0.47) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL191669 | 0.79 | FFAR1 (0.47) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL30641469 | 0.79 | FFAR1 (0.47) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL28253700 | 0.79 | FFAR1 (0.48) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL11034783 | 0.77 | KDM4E (0.49) | TSHRHSD17B10KDM4EALDH1A1HTT | |
| SCHEMBL8316908 | 0.77 | ACHE (0.42) | ALDH1A1HTTSMN1; SMN2FFAR1MEN1 | |
| SCHEMBL185558 | 0.77 | TP53 (0.43) | TSHRALDH1A1FFAR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338468-A | INTERMEDIATES FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338468-A | INTERMEDIATES FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338468-A | INTERMEDIATES FOR INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0008333-A1 | Alpha-prop-1-ynyl-3-phenoxybenzyl alcohols, their preparation and use as intermediate products in the preparation of pesticides | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | disclosed |