Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7366013 | 0.97 | KCNH2 (0.42) | TP53KCNH2CALM1SLC6A2TAAR1 | |
| SCHEMBL19896596 | 0.86 | PYCR1 (0.39) | KCNH2FFAR1FFAR4TSHRALDH1A1 | |
| SCHEMBL28568072 | 0.83 | KCNH2 (0.40) | TP53KCNH2CALM1SLC6A2TAAR1 | |
| SCHEMBL3888886 | 0.83 | CALM1 (0.50) | TP53KCNH2CALM1TAAR1FFAR1 | |
| SCHEMBL9856631 | 0.78 | CALM1 (0.45) | TP53KCNH2CALM1TAAR1FFAR1 | |
| SCHEMBL97491 | 0.78 | — | — | |
| SCHEMBL6319821 | 0.77 | KCNH2 (0.50) | TP53KCNH2CALM1FFAR1FFAR4 | |
| SCHEMBL17578919 | 0.77 | KCNH2 (0.44) | TP53KCNH2TAAR1FFAR1CYP1A2 | |
| SCHEMBL1453921 | 0.77 | KCNH2 (0.42) | TP53KCNH2CALM1TAAR1FFAR1 | |
| SCHEMBL11209706 | 0.77 | TSHR (0.48) | FFAR1CYP1A2TSHRALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977812-A | Method for synthesizing 1, 4-diphenyl-1-butyne derivatives by nickel catalytic reduction coupling | 华南理工大学 | 2025-05-13 | — | — | CN | claimed |
| CN-118852028-A | Nitrone pyrimidine ring compound and preparation method thereof | 南京工业大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118206417-A | Cobalt catalytic dehalogenation deuteration method | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | claimed |
| EP-1717223-B2 | Method for the purification of isocyanates | BASF SE (DE) | 2023-01-04 | — | — | EP | claimed |
| EP-1912953-B1 | PROCESS FOR THE SYNTHESIS OF ROSUVASTATIN CALCIUM | LEK PHARMACEUTICALS (SI) | 2016-08-17 | — | — | EP | claimed |
| EP-1717223-B1 | Method for the purification of isocyanates | BASF SE (DE) | 2016-07-20 | — | — | EP | claimed |
| US-7348396-B2 | Modified polyethylenephosphinic acids and their salts | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2008-03-25 | — | — | US | claimed |
| US-20070027297-A1 | Modified polyethylenephosphinic acids and their salts | CLARIANT FINANCE (BVI) LIMITED | 2007-02-01 | — | — | US | claimed |
| US-7045529-B2 | Imidazopyrimidinyl and imidazopyri dinyl derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-05-16 | — | — | US | claimed |
| US-20040229887-A1 | Novel imidazopyrimidinyl and imidazopyri dinyl derivatives | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-11-18 | — | — | US | claimed |
| US-6583315-B2 | Reacting yellow elemental phosphorus with an alkyl halide under alkaline conditions; acidifying, esterifying, isolating and hydrolyzing to obtain purified alkylphosphonous acid; reacting with acetylene | CLARIANT GMBH (DE) | 2003-06-24 | — | — | US | claimed |
| US-20030073865-A1 | PROCESS FOR PREPARING ETHANEBIS(ALKYLPHOSPHINIC) ACIDS | CLARIANT GMBH | 2003-04-17 | — | — | US | claimed |
| EP-1244666-A1 | IMIDAZOPYRIMIDINYL AND IMIDAZOPYRIDINYL DERIVATIVES | Bristol-Myers Squibb Pharma Company (US) | 2002-10-02 | — | — | EP | claimed |
| US-20020082447-A1 | Process for preparing ethylenediphosphonic acids | CLARIANT GMBH | 2002-06-27 | — | — | US | claimed |
| WO-2001044248-A1 | IMIDAZOPYRIMIDINYL AND IMIDAZOPYRIDINYL DERIVATIVES | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-21 | — | — | WO | claimed |
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0407341-B1 | Selective herbicidal agent | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | claimed |
| EP-0587823-A1 | USING THE IMMUNOACTIVATING ACTIVITY OF 3-NAPHTHYLOXY-2-HYDROXY-PROPYLAMINES, IN PARTICULAR FOR PROVIDING CELL IMMUNITY, E.G. AGAINST VIRAL INFECTIONS | PEUSCHEL, Karin, Elisabeth (CH) | 1994-03-23 | — | — | EP | claimed |
| WO-1993013049-A1 | USING THE IMMUNOACTIVATING ACTIVITY OF 3-NAPHTHYLOXY-2-HYDROXY-PROPYLAMINES, IN PARTICULAR FOR PROVIDING CELL IMMUNITY, E.G. AGAINST VIRAL INFECTIONS | PEUSCHEL KARIN ELISABETH (CH) | 1993-07-08 | — | — | WO | claimed |
| EP-0191025-B1 | N-6 AND 5'-N SUBSTITUTED CARBOXAMIDOADENOSINE DERIVATIVES AS CARDIAC VASODILATORS AND ANTIHYPERTENSIVE AGENTS, AND PROCESS FOR MAKING SAID COMPOUNDS | Whitby Research Incorporated (US) | 1990-03-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229887-A1 | Novel imidazopyrimidinyl and imidazopyri dinyl derivatives | CRH, GPR119, CRHR1 | TP53 4226/4885KCNH2 4450/4885CALM1 2132/4885 |
| US-20030073865-A1 | PROCESS FOR PREPARING ETHANEBIS(ALKYLPHOSPHINIC) ACIDS | HAO2, ARSA, APEH | TP53 3357/4885KCNH2 205/4885CALM1 3433/4885 |
| US-20020082447-A1 | Process for preparing ethylenediphosphonic acids | ENPP1, ALK, INPPL1 | TP53 3538/4885KCNH2 626/4885CALM1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.