SCHEMBL11209776

SCHEMBL11209776

COc1cc2nc(C)c(CS(=O)(=O)O)nc2cc1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.41
PGK1 P00558 5/20 0.40
MAPT P10636 3/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
G6PD P11413 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.37
STING1 Q86WV6 1/20 0.37
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
MAPK1 P28482 1/20 0.35
GLA P06280 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
ENPP1 P22413 2/20 0.34
SLC10A2 Q12908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11202172 0.81 PDE4A (0.47) NQO2PGK1MAPTPDE3BPDE3A
SCHEMBL11696562 0.77 PDE4A (0.54) NQO2PGK1MAPTGLAKDM4E
SCHEMBL11477391 0.76 NQO2 (0.46) NQO2PGK1MAPTPDE3BPDE3A
SCHEMBL11209291 0.75 KDM4E (0.42) MAPTNPC1LMNARAB9AGLA
SCHEMBL11211292 0.75 ALDH1A1 (0.40) MAPTNPC1LMNAPOLBRAB9A
SCHEMBL11207618 0.75 NQO2 (0.39) NQO2PGK1STING1PDE3BPDE3A
SCHEMBL346704 0.74 NQO2 (0.60) NQO2PGK1MAPTNPC1LMNA
SCHEMBL11203741 0.74 ENPP1 (0.38) NQO2PGK1PDE3BPDE3AENPP1
SCHEMBL11211327 0.70
SCHEMBL650718 0.70 NQO2 (0.50) NQO2PGK1MAPTPDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed