Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11212033 | 0.99 | PARP1 (0.37) | HSD17B10NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11271082 | 0.80 | PBRM1 (0.46) | HSD17B10NPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL10332163 | 0.79 | KDM4E (0.47) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL11264396 | 0.79 | F2 (0.46) | HSD17B10NPC1SMN1; SMN2KDM4EPRSS1 | |
| SCHEMBL10807467 | 0.77 | GABRR1 (0.52) | HSD17B10NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11268681 | 0.74 | ALDH1A1 (0.55) | MAPTRAB9ASMN1; SMN2PRSS1PRSS2 | |
| SCHEMBL11208323 | 0.73 | ADRB2 (0.46) | HSD17B10NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21792030 | 0.73 | ALDH1A1 (0.59) | HSD17B10NPC1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL11276213 | 0.72 | ADRB2 (0.45) | HSD17B10NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2566629 | 0.72 | PARP1 (0.61) | PARP1PARP10PARP14KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323688-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| US-4322431-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |