SCHEMBL112098

SCHEMBL112098

O=C(O)C(Cc1ccc(O)cc1)N1C(=O)CCC1=O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.77
PKM P14618 1/20 0.77
POLB P06746 2/20 0.64
KMT2A Q03164 3/20 0.57
CYP2D6 P10635 1/20 0.57
MEN1 O00255 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
GAA P10253 1/20 0.50
SLC7A5 Q01650 1/20 0.49
AADAT Q8N5Z0 1/20 0.46
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5010177 1.00 ALDH1A1 (0.77) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL592660 0.90 POLB (0.64) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL2304471 0.87 ALDH1A1 (1.00) ALDH1A1PKMPOLBKMT2AMEN1
SCHEMBL1563867 0.87 ALDH1A1 (1.00) ALDH1A1PKMPOLBKMT2AMEN1
SCHEMBL2307309 0.86 ALDH1A1 (0.74) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL7033312 0.83 ALDH1A1 (0.74) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL6386661 0.82 ALDH1A1 (0.90) ALDH1A1PKMPOLBKMT2AMEN1
SCHEMBL11688646 0.82 ALDH1A1 (0.52) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL3073609 0.81 ALDH1A1 (0.51) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL11257389 0.81 ALDH1A1 (0.62) ALDH1A1PKMPOLBKMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025046227-A1 X-RAY VISIBLE IMPLANTABLE SCAFFOLDS UCL BUSINESS LTD (GB) 2025-03-06 WO claimed
WO-2021153823-A1 METHOD FOR PREPARING CHITOSAN HYDROGEL-CHELATOR FOR CANCER THERAPY (주)카이바이오텍 2021-08-05 WO claimed
US-7282342-B2 Methods for detecting weakly immunogenic analytes NEUREN PHARMACEUTICALS LTD. (NZ) 2007-10-16 US claimed
US-20070128660-A1 Methods for detecting weakly immunogenic analytes NEUREN PHARMACEUTICALS LTD. (NZ) 2007-06-07 US claimed
US-20060035279-A1 Anti-GPE antibodies, their uses and assays for weakly immunogenic molecules NEUREN PHARMACEUTICALS LTD. (NZ) 2006-02-16 US claimed
EP-0220858-B1 MONOCLONAL ANTI-HUMAN BREAST CANCER ANTIBODIES, CORRESPONDING HYBRIDOMAS, THE PRODUCTION AND USE THEREOF CETUS CORP (US) 1993-02-10 EP claimed
US-4938948-A Diagnosis CETUS CORPORATION (US) 1990-07-03 US claimed
EP-0220858-A2 Monoclonal anti-human breast cancer antibodies, corresponding hybridomas, the production and use thereof CETUS ONCOLOGY CORPORATION (US) 1987-05-06 EP claimed
US-20260146092-A1 DUAL SPECIFICITY ANTIBODIES TO HUMAN PD-L1 AND PD-L2 AND METHODS OF USE THEREFOR BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-28 US disclosed
WO-2026102432-A1 HUMAN ANTIBODIES TO MARBURG VIRUS AND METHODS OF USE THEREFOR VANDERBILT UNIVERSITY (US) 2026-05-15 WO disclosed
EP-4731640-A1 IMMUNOREACTIVE PEPTIDES Research Development Foundation (US) 2026-04-29 EP disclosed
EP-4720675-A2 HUMAN MONOCLONAL ANTIBODIES FOR HUMAN PARAINFLUENZA VIRUS TYPE 3 Vanderbilt University (US) 2026-04-08 EP disclosed
EP-4698566-A2 AGNONISTIC ANTIBODIES TARGETING JAML La Jolla Institute for Immunology (US) 2026-02-25 EP disclosed
US-12559545-B2 Human hendra virus and nipah virus antibodies and methods of use therefor VANDERBILT UNIVERSITY (US) 2026-02-24 US disclosed
US-4722899-A INDUCE IMMUNOLOGICAL TOLERANCE TO SECOND ANTIGEN THEN IMMUNIZING WITH FIRST ANTIGEN Hamaoka, Toshiyuki (JP) 1988-02-02 US disclosed
EP-0203764-A2 Radiohalogenated small molecules for protein labeling NEORX CORPORATION (US) 1986-12-03 EP disclosed
EP-0181061-A1 Labelling organic molecules with sulphur-35 AMERSHAM INTERNATIONAL plc (GB) 1986-05-14 EP disclosed
EP-0063373-B1 CELL-SPECIFIC GLYCOPEPTIDE LIGANDS MERCK & CO. INC. (US) 1986-03-12 EP disclosed
US-4386026-A Cell-specific glycopeptide ligands MERCK & CO., INC. (US) 1983-05-31 US disclosed
EP-0063373-A1 Cell-specific glycopeptide ligands MERCK & CO. INC. (US) 1982-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146092-A1 DUAL SPECIFICITY ANTIBODIES TO HUMAN PD-L1 AND PD-L2 AND METHODS OF USE THEREFOR PDCD1LG2, PDCD1, CD274 ALDH1A1 2835/4885PKM 3343/4885POLB 2738/4885
US-12559545-B2 Human hendra virus and nipah virus antibodies and methods of use therefor VSIG8, IGSF11, NIPSNAP1 ALDH1A1 3333/4885PKM 4775/4885POLB 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.