SCHEMBL5010177

SCHEMBL5010177

O=C(O)[C@H](Cc1ccc(O)cc1)N1C(=O)CCC1=O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.77
PKM P14618 1/20 0.77
POLB P06746 2/20 0.64
KMT2A Q03164 3/20 0.57
CYP2D6 P10635 1/20 0.57
MEN1 O00255 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
GAA P10253 1/20 0.50
SLC7A5 Q01650 1/20 0.49
AADAT Q8N5Z0 1/20 0.46
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112098 1.00 ALDH1A1 (0.77) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL592660 0.90 POLB (0.64) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL2304471 0.87 ALDH1A1 (1.00) ALDH1A1PKMPOLBKMT2AMEN1
SCHEMBL1563867 0.87 ALDH1A1 (1.00) ALDH1A1PKMPOLBKMT2AMEN1
SCHEMBL2307309 0.86 ALDH1A1 (0.74) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL7033312 0.83 ALDH1A1 (0.74) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL6386661 0.82 ALDH1A1 (0.90) ALDH1A1PKMPOLBKMT2AMEN1
SCHEMBL11688646 0.82 ALDH1A1 (0.52) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL3073609 0.81 ALDH1A1 (0.51) ALDH1A1PKMPOLBKMT2ACYP2D6
SCHEMBL11257389 0.81 ALDH1A1 (0.62) ALDH1A1PKMPOLBKMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113144210-A Antibacterial polypeptide compound and preparation method and application thereof 梅奥(浙江)细胞工程有限责任公司 2021-07-23 CN claimed
EP-1284978-B2 PROCESS FOR THE PURIFICATION OF A SALT OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 2008-09-10 EP claimed
US-7087748-B2 Process SMITHKLINE BEECHAM P.L.C. (GB) 2006-08-08 US claimed
EP-1319086-B1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 2004-11-03 EP claimed
EP-1284978-B1 PROCESS FOR THE PURIFICATION OF A SALT OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 2004-08-18 EP claimed
US-20040063930-A1 Selective adsorption SMITHKLINE BEECHAM P.L.C. (GB) 2004-04-01 US claimed
JP-2004509136-A 2004-03-25 JP claimed
EP-1319086-A1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 2003-06-18 EP claimed
WO-2002022846-A1 PROCESS SMITHKLINE BEECHAM P.L.C. (GB) 2002-03-21 WO claimed
CN-118147247-A Food flavoring compound succinyl amino acid and preparation method thereof 华南理工大学 2024-06-07 CN disclosed
CN-113144210-A Antibacterial polypeptide compound and preparation method and application thereof 梅奥(浙江)细胞工程有限责任公司 2021-07-23 CN disclosed
US-7087748-B2 Process SMITHKLINE BEECHAM P.L.C. (GB) 2006-08-08 US disclosed
US-6830863-B2 Image-receiving sheet having image-receiving layer and four thermal transfer sheets each including a support, a light-to-heat converting layer and an image-forming layer, in which each of the sheets has a different color FUJI PHOTO FILM CO., LTD. (JP) 2004-12-14 US disclosed
EP-1319086-B1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 2004-11-03 EP disclosed
WO-2002022846-A1 PROCESS SMITHKLINE BEECHAM P.L.C. (GB) 2002-03-21 WO disclosed
WO-2001087891-A1 PROCESS FOR THE PURIFICATION OF A SALT OF CLAVULANIC ACID SMITHKLINE BEECHAM P.L.C. (GB) 2001-11-22 WO disclosed
EP-0764167-A4 BICYCLING LACTAM INHIBITOR OF INTERLEUKIN-1-BETA CONVERTING ENZYME SANOFI WINTHROP INC (US) 1997-09-17 EP disclosed
EP-0764167-A1 BICYCLING LACTAM INHIBITOR OF INTERLEUKIN-1-BETA CONVERTING ENZYME SANOFI WINTHROP, INC. (US) 1997-03-26 EP disclosed
WO-1995033751-A1 BICYCLING LACTAM INHIBITOR OF INTERLEUKIN-1-BETA CONVERTING ENZYME SANOFI WINTHROP, INC. (US) 1995-12-14 WO disclosed
US-4839068-A OIL ADDITIVES FOR MINERAL OIL LUBRICANTS; FRICTION RESISTANCE' VISCOSITY IMPROVERS; FILM-FORMERS; INTERNAL COMBUSTION ENGINES THE LUBRIZOL CORPORATION (US) 1989-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063930-A1 Selective adsorption GMPS, ITPA, TET2 ALDH1A1 412/4885PKM 3573/4885POLB 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.