Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563867 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL6386661 | 0.95 | ALDH1A1 (0.90) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL7334247 | 0.87 | ALDH1A1 (0.77) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL112098 | 0.87 | ALDH1A1 (0.77) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL5010177 | 0.87 | ALDH1A1 (0.77) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL2307309 | 0.85 | ALDH1A1 (0.74) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL7033312 | 0.85 | ALDH1A1 (0.74) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL2308311 | 0.85 | ALDH1A1 (0.73) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL7523260 | 0.83 | ALDH1A1 (0.70) | ALDH1A1PKMGAAKMT2AHSD17B10 | |
| SCHEMBL9650037 | 0.83 | ALDH1A1 (0.70) | ALDH1A1PKMGAAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272292-B | (2, 5-dioxopyrrolidin-1-yl) (phenyl) -acetamide derivatives and their use in the treatment of neurological diseases | 雅盖隆大学 | 2024-04-12 | — | — | CN | disclosed |
| EP-3908580-A1 | (2,5-DIOXOPYRROLIDIN-1-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | UNIWERSYTET JAGIELLONSKI (PL) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020145831-A1 | (2,5-DIOXOPYRROLIDIN-L-YL)(PHENYL)-ACETAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES | Uniwersytet Jagielloński (PL) | 2020-07-16 | — | — | WO | disclosed |
| US-10167365-B2 | Polymer and composition | DSM IP ASSETS B.V. (NL) | 2019-01-01 | — | — | US | disclosed |
| EP-2351848-B1 | METHOD FOR PRODUCING L-AMINO ACID | KANEKA CORP (JP) | 2018-02-28 | — | — | EP | disclosed |
| EP-3055340-B1 | POLYMER AND COMPOSITION | DSM IP ASSETS BV (NL) | 2017-11-22 | — | — | EP | disclosed |
| US-9464306-B2 | Method for producing L-amino acid | KANEKA CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20160237213-A1 | POLYMER AND COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2016-08-18 | — | — | US | disclosed |
| US-20160237213-A1 | POLYMER AND COMPOSITION | COVESTRO (NETHERLANDS) B.V. (NL) | 2016-08-18 | — | — | US | disclosed |
| WO-2015052342-A1 | POLYMER AND COMPOSITION | DSM IP ASSETS B.V. (NL) | 2015-04-16 | — | — | WO | disclosed |
| US-8728771-B2 | L-succinylaminoacylase and process for producing L-amino acid using it | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20140117280-A1 | OXYGEN ABSORBER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-05-01 | — | — | US | disclosed |
| US-20140117280-A1 | OXYGEN ABSORBER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-05-01 | — | — | US | disclosed |
| EP-2711077-A1 | OXYGEN ABSORBER | Mitsubishi Gas Chemical Company, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-20110250653-A1 | L-SUCCINYLAMINOACYLASE AND PROCESS FOR PRODUCING L-AMINO ACID USING IT | SEKISUI MEDICAL CO., LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| US-20110229940-A1 | METHOD FOR PRODUCING L-AMINO ACID | KANEKA CORPORATION (JP) | 2011-09-22 | — | — | US | disclosed |
| EP-2351848-A1 | METHOD FOR PRODUCING L-AMINO ACID | Kaneka Corporation (JP) | 2011-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229940-A1 | METHOD FOR PRODUCING L-AMINO ACID | ADSL, ASNS, AASDHPPT | ALDH1A1 895/4885PKM 1778/4885GAA 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.