SCHEMBL11209899

SCHEMBL11209899

Cc1nc2cc3c(cc2nc1CO)OCO3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.40
HPGD P15428 7/20 0.40
LMNA P02545 6/20 0.40
KDM4E B2RXH2 5/20 0.40
SMN1; SMN2 Q16637 5/20 0.40
RAB9A P51151 5/20 0.40
HSD17B10 Q99714 2/20 0.40
ATM Q13315 1/20 0.40
MAPT P10636 4/20 0.38
RPS6KB2 Q9UBS0 1/20 0.37
NPC1 O15118 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
RXFP1 Q9HBX9 2/20 0.36
PKM P14618 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11204856 0.90 GAA (0.40) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL11483166 0.83 ALDH1A1 (0.40) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL11208689 0.81 ALDH1A1 (0.49) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL11211292 0.81 ALDH1A1 (0.40) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL11215050 0.76
SCHEMBL6190994 0.73 ALDH1A1 (0.43) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL11202172 0.73 PDE4A (0.47) ALDH1A1KDM4ESMN1; SMN2MAPTRPS6KB2
SCHEMBL11209291 0.71 KDM4E (0.42) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL16424551 0.70 LMNA (0.51) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2
SCHEMBL11203726 0.69 RPS6KB2 (0.46) ALDH1A1HPGDLMNAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed