Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212844 | 0.87 | POLB (0.40) | SMN1; SMN2TDP1POLBALDH1A1GAA | |
| SCHEMBL11213302 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1L3MBTL1HPGDCYP3A4 | |
| SCHEMBL11220278 | 0.82 | CYP4F2 (0.46) | CYP4F2CYP4A11HPGDDPP4POLB | |
| Hydrochloric Acid SCHEMBL6983711 | 0.81 | CYP4F2 (0.48) | CYP4F2CYP4A11SMN1; SMN2TDP1HPGD | |
| SCHEMBL11210138 | 0.80 | CYP4F2 (0.43) | CYP4F2CYP4A11HPGDDPP4POLB | |
| SCHEMBL6036442 | 0.77 | POLB (0.56) | CYP4F2CYP4A11TDP1L3MBTL1HPGD | |
| SCHEMBL491048 | 0.76 | CYP1A2 (0.55) | CYP4F2CYP4A11SMN1; SMN2DPP4ALDH1A1 | |
| SCHEMBL11214621 | 0.75 | CYP4F2 (0.59) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11212268 | 0.75 | ALOX5 (0.55) | CYP4F2CYP4A11ALDH1A1TNFKMT2A | |
| SCHEMBL11214518 | 0.75 | ALDH1A1 (0.46) | SMN1; SMN2TDP1HPGDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |