Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213302 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL10268696 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL11212844 | 0.84 | POLB (0.40) | ALDH1A1GAAGFERKDM4EMAPT | |
| SCHEMBL4970416 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EMAPTRECQL | |
| SCHEMBL11210532 | 0.75 | CYP4F2 (0.44) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL12270110 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAAGFERKDM4EHPGD | |
| SCHEMBL5093783 | 0.74 | ALDH1A1 (0.67) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL29749375 | 0.73 | ALDH1A1 (0.49) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL10268521 | 0.73 | ALDH1A1 (0.49) | ALDH1A1GAAGFERHSP90AB1KDM4E | |
| SCHEMBL4034916 | 0.73 | MTNR1A (0.56) | ALDH1A1GAAGFERKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |