Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799301 | 0.91 | PTGIR (0.51) | SIGMAR1TSHR | |
| SCHEMBL11212858 | 0.90 | FDPS (0.46) | ALDH1A1 | |
| SCHEMBL9799418 | 0.87 | TAAR1 (0.46) | AOC3SIGMAR1ALDH1A1TSHR | |
| SCHEMBL9799416 | 0.85 | CDK8 (0.43) | SIGMAR1ALDH1A1TSHRCHRM2HTR1A | |
| SCHEMBL9799179 | 0.84 | TACR1 (0.46) | SIGMAR1ALOX5ALDH1A1TSHR | |
| SCHEMBL6466553 | 0.84 | AOC3 (0.47) | AOC3SIGMAR1ALOX5CHRM2HTR1A | |
| SCHEMBL6468346 | 0.78 | CCR6 (0.45) | AOC3SIGMAR1ALOX5ALDH1A1 | |
| SCHEMBL7047948 | 0.77 | L3MBTL1 (0.43) | AOC3SIGMAR1ALOX5 | |
| SCHEMBL829335 | 0.75 | ALOX5 (0.61) | ALOX5ALDH1A1ADRA1ASLC6A3 | |
| SCHEMBL4456605 | 0.75 | SMN1; SMN2 (0.52) | ALOX5ALDH1A1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040859-B1 | N'-PHENYL-N-METHYLUREA DERIVATIVES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | disclosed |
| EP-0040859-A1 | N'-phenyl-N-methylurea derivatives, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-12-02 | — | — | EP | disclosed |