Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL11206225 | 1.00 | LMNA (0.50) | LMNAMAPK1ADRB2CYP2C9MEN1 | |
| SCHEMBL29903923 | 0.88 | LMNA (0.62) | LMNAMAPK1CYP2C9MEN1CYP2D6 | |
| SCHEMBL6367 | 0.88 | LMNA (0.62) | LMNAMAPK1CYP2C9MEN1CYP2D6 | |
| SCHEMBL6366 | 0.88 | LMNA (0.62) | LMNAMAPK1CYP2C9MEN1CYP2D6 | |
| SCHEMBL2163167 | 0.88 | LMNA (0.62) | LMNAMAPK1CYP2C9MEN1CYP2D6 | |
| SCHEMBL11652701 | 0.86 | LMNA (0.60) | LMNAMAPK1CYP2C9MEN1CYP2D6 | |
| 1,4-Dichlorobenzene SCHEMBL28066584 | 0.86 | ADRB2 (0.52) | LMNAADRB2CYP2C9MEN1CYP2D6 | |
| 1,4-Dichlorobenzene SCHEMBL27939236 | 0.86 | ADRB2 (0.52) | LMNAADRB2CYP2C9MEN1CYP2D6 | |
| Deaminohydroxyvaline SCHEMBL9069626 | 0.85 | LMNA (0.50) | LMNAMAPK1ADRB2CYP2C9MEN1 | |
| D-Alanine SCHEMBL11207612 | 0.83 | LMNA (0.52) | LMNAMAPK1BLMTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |