Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29302948 | 0.85 | KDM4E (0.40) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL29879837 | 0.85 | KDM4E (0.40) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| Bicarbonate SCHEMBL29136788 | 0.81 | KDM4E (0.38) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6081939 | 0.78 | LMNA (0.51) | L3MBTL1ALDH1A1HTTTSHRMEN1 | |
| SCHEMBL15978552 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HTTTSHRMEN1 | |
| SCHEMBL15977383 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HTTTSHRMEN1 | |
| SCHEMBL15977390 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HTTTSHRMEN1 | |
| SCHEMBL6081343 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HTTTSHRMEN1 | |
| SCHEMBL15978556 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HTTTSHRMEN1 | |
| SCHEMBL16019176 | 0.75 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1HTTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015604-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITION OF LIPOGENESIS IN MAMMALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-02-23 | — | — | EP | disclosed |
| EP-0015604-A1 | Compounds and compositions for use in inhibition of lipogenesis in mammals | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-09-17 | — | — | EP | disclosed |
| US-4202902-A | VETERINARY MEDICINE | SHELL OIL COMPANY (US) | 1980-05-13 | — | — | US | disclosed |