Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937151 | 0.81 | MEN1 (0.44) | MAPTLMNAMAPK1HTTTSHR | |
| SCHEMBL25902691 | 0.76 | KMT2A (0.54) | MAPTLMNAMAPK1HTTTSHR | |
| SCHEMBL29765677 | 0.75 | CES2 (0.59) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL158348 | 0.75 | CES2 (0.59) | MAPTLMNAGAAKDM4EMEN1 | |
| SCHEMBL5155478 | 0.74 | AKR1C3 (0.62) | MAPTGAAKDM4EMEN1USP2 | |
| SCHEMBL5389980 | 0.74 | GAA (0.68) | MAPTLMNAMAPK1HTTTSHR | |
| SCHEMBL5155352 | 0.74 | KDM4E (0.68) | MAPTGAAKDM4EMEN1USP2 | |
| SCHEMBL30070815 | 0.74 | GAA (0.68) | MAPTLMNAMAPK1HTTTSHR | |
| SCHEMBL10935425 | 0.73 | ELANE (0.47) | MAPTLMNAMAPK1HTTTSHR | |
| SCHEMBL11638597 | 0.72 | MAPT (0.49) | MAPTGAAKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085265-A1 | Process for the preparation of alpha,alpha-difluoroalkoxy or alpha,alpha-difluoroalkylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-10 | — | — | EP | disclosed |