Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321927 | 0.87 | LMNA (0.43) | MEN1KMT2AKDM4EGAAUSP2 | |
| SCHEMBL1127676 | 0.82 | KDM4E (0.45) | MEN1KMT2AKDM4EGAAUSP2 | |
| SCHEMBL11211368 | 0.81 | MAPT (0.54) | MEN1KMT2AKDM4EGAAUSP2 | |
| SCHEMBL4070485 | 0.81 | KEAP1 (0.48) | MEN1KMT2AKDM4EUSP2KEAP1 | |
| SCHEMBL4109829 | 0.81 | KDM4E (0.44) | MEN1KMT2AKDM4EGAAUSP2 | |
| SCHEMBL11752106 | 0.80 | SLC6A9 (0.47) | KDM4EUSP2MAPTRAB9AMAPK1 | |
| SCHEMBL8578095 | 0.79 | AKR1C3 (0.55) | MEN1KMT2AGAAMAPTRAB9A | |
| SCHEMBL28305846 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EGAAUSP2 | |
| SCHEMBL11761193 | 0.78 | ALDH1A1 (0.66) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL29765677 | 0.78 | CES2 (0.59) | MEN1KMT2AKDM4EGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085265-B1 | PROCESS FOR THE PREPARATION OF ALPHA,ALPHA-DIFLUOROALKOXY OR ALPHA,ALPHA-DIFLUOROALKYLTHIOPHENYL KETONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-22 | — | — | EP | disclosed |