SCHEMBL112115

SCHEMBL112115

CCCCCC(Oc1ccc(C(=N)N)cc1)Oc1ccc(C(=N)N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 9/20 0.51
PRSS2 P07478 2/20 0.51
PRSS3 P35030 2/20 0.51
TMPRSS2 O15393 2/20 0.49
PRMT1 Q99873 3/20 0.47
F2 P00734 3/20 0.47
ST14 Q9Y5Y6 3/20 0.47
PLAU P00749 2/20 0.47
PRMT5 O14744 1/20 0.47
SLC22A2 O15244 1/20 0.47
SLC22A1 O15245 1/20 0.47
PTP4A3 O75365 1/20 0.47
SLC22A3 O75751 1/20 0.47
F10 P00742 1/20 0.47
PLG P00747 1/20 0.47
S100B P04271 1/20 0.47
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM5 P08912 1/20 0.47
ADRA2A P08913 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7475217 0.95 PRSS1 (0.53) PRSS1PRSS2PRSS3TMPRSS2PRMT1
SCHEMBL6724722 0.82 PRSS1 (0.59) PRSS1PRSS2PRSS3TMPRSS2PRMT1
SCHEMBL10430533 0.80 PRSS1 (0.44) PRSS1PRSS2PRSS3TMPRSS2PRMT1
SCHEMBL1445548 0.79 TP53 (0.59)
Hydrochloric Acid SCHEMBL9428095 0.79 PRSS1 (0.46) PRSS1PRSS2PRSS3TMPRSS2PRMT1
SCHEMBL10595641 0.78 TDP1 (0.44) OPRM1
SCHEMBL2181006 0.78 TP53 (0.62)
SCHEMBL2183384 0.78 TP53 (0.62)
SCHEMBL9860125 0.78 TP53 (0.62)
SCHEMBL113925 0.77 F2 (0.56) PRSS1F2ST14PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387448-A1 NOVEL PESTICIDAL COMPOSITION Doshi, Hiteshkumar Anilkant (IN) 2024-06-26 EP disclosed
EP-4247185-A1 LIQUID COMPOSITION COMPRISING CEREAL BETA-GLUCAN OR A CEREAL EXTRACT COMPRISING BETA-GLUCAN Symrise AG (DE) 2023-09-27 EP disclosed
WO-2023021461-A1 NOVEL PESTICIDAL COMPOSITION DOSHI HITESHKUMAR ANILKANT (IN) 2023-02-23 WO disclosed
EP-4114348-A1 COMPOSITION COMPRISING AN AVENTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY Symrise AG (DE) 2023-01-11 EP disclosed
EP-4114354-A1 AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE Symrise AG (DE) 2023-01-11 EP disclosed
EP-4114350-A1 COMPOSITION COMPRISING AN AVENANTHRAMIDE WITH IMPROVED SKIN PENETRATION Symrise AG (DE) 2023-01-11 EP disclosed
EP-4114349-A1 COMPOSITION OR OAT EXTRACT COMPRISING AVENANTHRAMIDE AND BETA-GLUCAN Symrise AG (DE) 2023-01-11 EP disclosed
WO-2022105985-A1 LIQUID COMPOSITION COMPRISING CEREAL BETA-GLUCAN OR A CEREAL EXTRACT COMPRISING BETA-GLUCAN SYMRISE AG (DE) 2022-05-27 WO disclosed
EP-3986365-A1 SURFACTANT CONTAINING FORMULATION OF PSEUDO-CERAMIDES Symrise AG (DE) 2022-04-27 EP disclosed
EP-3986360-A1 PRODUCT FOR DYEING KERATINOUS MATERIAL, CONTAINING AMINOSILICONE, A CHROMOPHORIC COMPOUND, PRESERVATIVE AND A FATTY CONSTITUENT Henkel AG & Co. KGaA (DE) 2022-04-27 EP disclosed
EP-1605981-A1 HEMORRHOID TREATMENT PAD THE PROCTER & GAMBLE COMPANY (US) 2005-12-21 EP disclosed
EP-1478231-A1 SYNERGISTIC MIXTURES OF 1,2-ALKANE DIOLS Symrise GmbH & Co. KG (DE) 2004-11-24 EP disclosed
WO-2004073757-A1 HEMORRHOID TREATMENT PAD THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
EP-1432457-A1 SANITARY NAPKINS WITH HYDROPHOBIC LOTIONS THE PROCTER & GAMBLE COMPANY (US) 2004-06-30 EP disclosed
WO-2003069994-A1 SYNERGISTIC MIXTURES OF 1,2-ALKANE DIOLS SYMRISE GMBH & CO. KG (DE) 2003-08-28 WO disclosed
WO-2003028776-A1 SANITARY NAPKINS WITH HYDROPHOBIC LOTIONS THE PROCTER & GAMBLE COMPANY (US) 2003-04-10 WO disclosed
EP-1212097-A2 ENZYME INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2002-06-12 EP disclosed
EP-1212034-A1 ENZYME INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2002-06-12 EP disclosed
WO-2001017564-A2 ENZYME INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2001-03-15 WO disclosed
WO-2001017501-A1 ENZYME INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2001-03-15 WO disclosed