Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.49 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | S100B | P04271 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112115 | 0.95 | PRSS1 (0.51) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL6724722 | 0.83 | PRSS1 (0.59) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL2180724 | 0.79 | TP53 (0.57) | — | |
| SCHEMBL5302657 | 0.78 | PRSS1 (0.44) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL11229331 | 0.78 | LTA4H (0.52) | CHRM2CHRM5ADRA2ACYP2D6ACHE | |
| SCHEMBL2535207 | 0.78 | TDP1 (0.45) | — | |
| SCHEMBL9650651 | 0.78 | PRSS1 (0.81) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| Hydrochloric Acid SCHEMBL11182186 | 0.76 | PRSS1 (0.82) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL6865149 | 0.76 | TSHR (0.50) | — | |
| SCHEMBL10430533 | 0.76 | PRSS1 (0.44) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242059-A2 | NOVEL PRODRUGS FOR ANTIMICROBIAL AMIDINES | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003685-A2 | NOVEL PRODRUGS FOR ANTIMICROBIAL AMIDINES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2001-01-18 | — | — | WO | disclosed |