SCHEMBL6724722

SCHEMBL6724722

CCC(Oc1ccc(C(=N)N)cc1)Oc1ccc(C(=N)N)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 8/20 0.59
PRSS2 P07478 2/20 0.59
PRSS3 P35030 2/20 0.59
F2 P00734 3/20 0.53
ST14 Q9Y5Y6 3/20 0.53
PLAU P00749 2/20 0.53
TMPRSS2 O15393 2/20 0.52
PRMT1 Q99873 3/20 0.50
PRMT5 O14744 1/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
PTP4A3 O75365 1/20 0.50
SLC22A3 O75751 1/20 0.50
F10 P00742 1/20 0.50
PLG P00747 1/20 0.50
S100B P04271 1/20 0.50
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM5 P08912 1/20 0.50
ADRA2A P08913 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7475217 0.83 PRSS1 (0.53) PRSS1PRSS2PRSS3F2ST14
SCHEMBL112115 0.82 PRSS1 (0.51) PRSS1PRSS2PRSS3F2ST14
SCHEMBL19486253 0.80 SMN1; SMN2 (0.58) PRSS1PRSS2PRSS3F2ST14
SCHEMBL19489229 0.80 SMN1; SMN2 (0.58) PRSS1PRSS2PRSS3F2ST14
SCHEMBL19486247 0.80 SMN1; SMN2 (0.58) PRSS1PRSS2PRSS3F2ST14
SCHEMBL13716165 0.79 PARP10 (0.66) PRSS1PRSS2PRSS3F2ST14
SCHEMBL6732601 0.78 PRSS1 (0.44) PRSS1PRSS2PRSS3F2ST14
Hydrochloric Acid SCHEMBL9508544 0.77 PARP10 (0.63) PRSS1PRSS2PRSS3F2ST14
SCHEMBL4992394 0.76 PRSS1 (0.60) PRSS1PRSS2PRSS3F2ST14
SCHEMBL29433602 0.76 PRSS1 (0.57) PRSS1PRSS2PRSS3F2ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673756-B2 MULTILAYER; CUTTING, JOINING UNDER PRESSURE SYMRISE GMBH & CO. KG (DE) 2004-01-06 US disclosed
US-20020173436-A1 Multilayer; cutting, joining under pressure SYMRISE GMBH & CO. KG (DE) 2002-11-21 US disclosed