Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608098 | 1.00 | ACHE (0.81) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL874376 | 1.00 | ACHE (0.81) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL23252415 | 0.92 | ACHE (0.68) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL16716051 | 0.92 | ACHE (0.68) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL12386341 | 0.92 | ACHE (0.68) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL11887 | 0.90 | — | — | |
| SCHEMBL8469646 | 0.90 | ACHE (1.00) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| Benzidine SCHEMBL28531320 | 0.87 | ACHE (0.62) | ACHEALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL1439188 | 0.87 | — | — | |
| SCHEMBL6463424 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399210-A | O-NAPHTHOQUINONEDIAZIDE AND A DISCOLORING AGENT | FUJI PHOTO FILM COMPANY LTD. (JP) | 1983-08-16 | — | — | US | disclosed |