SCHEMBL874376

SCHEMBL874376

Cc1ccc(-c2ccc(N)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.81
ALDH1A1 P00352 5/20 0.69
TDP1 Q9NUW8 4/20 0.69
TP53 P04637 4/20 0.69
CYP3A4 P08684 2/20 0.69
TEAD4 Q15561 1/20 0.59
MAPT P10636 7/20 0.56
POLB P06746 1/20 0.56
HSD17B10 Q99714 3/20 0.55
TAAR1 Q96RJ0 1/20 0.55
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
SMN1; SMN2 Q16637 5/20 0.47
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
TSHR P16473 1/20 0.47
KIF11 P52732 2/20 0.46
KDM4E B2RXH2 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL11211665 1.00 ACHE (0.81) ACHEALDH1A1TDP1TP53CYP3A4
SCHEMBL2608098 1.00 ACHE (0.81) ACHEALDH1A1TDP1TP53CYP3A4
SCHEMBL23252415 0.92 ACHE (0.68) ACHEALDH1A1TDP1TP53CYP3A4
SCHEMBL16716051 0.92 ACHE (0.68) ACHEALDH1A1TDP1TP53CYP3A4
SCHEMBL12386341 0.92 ACHE (0.68) ACHEALDH1A1TDP1TP53CYP3A4
SCHEMBL11887 0.90
SCHEMBL8469646 0.90 ACHE (1.00) ACHEALDH1A1TDP1TP53CYP3A4
Benzidine SCHEMBL28531320 0.87 ACHE (0.62) ACHEALDH1A1TDP1TP53CYP3A4
SCHEMBL1439188 0.87
SCHEMBL6463424 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107459535-A Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof 南京工业大学 2017-12-12 CN claimed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
US-20250289781-A1 TRIFLUOROMETHANESULFONYLATING AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND OR TRIFLUOROMETHANESULFONYL COMPOUND CENTRAL GLASS COMPANY, LIMITED (JP) 2025-09-18 US disclosed
EP-4308628-B1 ALKYD RESIN, COATING COMPOSITION, AND SUBSTRATE COATED WITH SUCH COATING COMPOSITON AKZO NOBEL COATINGS INT BV (NL) 2025-04-30 EP disclosed
CN-113727972-B Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof 韩国科学技术研究院 2024-12-27 CN disclosed
CN-119137096-A Trifluoromethanesulfonyl a composition of the agent trifluoromethanesulfonyl oxy compounds or Process for producing trifluoromethanesulfonyl compound 中央硝子株式会社 2024-12-13 CN disclosed
US-12054582-B2 Alkyd resin, coating composition, and substrate coated with such coating composition AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2024-08-06 US disclosed
CN-117098795-B Alkyd resin, coating composition and substrate coated with the coating composition 阿克佐 诺贝尔国际涂料股份有限公司 2024-07-19 CN disclosed
EP-4400559-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND Samsung Display Co., Ltd. (KR) 2024-07-17 EP disclosed
EP-4395499-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2024-07-03 EP disclosed
US-5877278-A SOLID PHASE SYNTHESIS USING TWO SUBMONOMERS-AN ACYLATING AGENT, E.G. A HALOACETIC ACID, AND A PRIMARY AMINE; CYCLIZATION TO PRODUCE MIMETICS OF DRUGS; ELIMINATION OF THE NECESSITY OF PROTECTION GROUPS CHIRON CORPORATION (US) 1999-03-02 US disclosed
US-5831005-A ACYLATION, NUCLEOPHILIC DISPLACEMENT CYCLES CHIRON CORPORATION (US) 1998-11-03 US disclosed
EP-0789577-A4 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORP (US) 1998-07-22 EP disclosed
EP-0805143-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC THIN FILM, AND TRIAMINE COMPOUNDS IDEMITSU KOSAN COMPANY LIMITED (JP) 1997-11-05 EP disclosed
EP-0789577-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1997-08-20 EP disclosed
WO-1996040202-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1996-12-19 WO disclosed
US-5480871-A TREATMENT OF BENIGN PROSTATIC HYPERPLASIA CHIRON CORPORATION (US) 1996-01-02 US disclosed
US-5447916-A Hypotensive agents CHIRON CORPORATION (US) 1995-09-05 US disclosed
WO-1995004072-A1 PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS CHIRON CORPORATION (US) 1995-02-09 WO disclosed
WO-1995001334-A1 ARYLAMINE-DERIVED INDOLE COMPOUNDS AS SELECTIVE 5HT1D AND 5HT1B RECEPTOR LIGANDS PIERRE FABRE MEDICAMENT (FR) 1995-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289781-A1 TRIFLUOROMETHANESULFONYLATING AGENT COMPOSITION AND METHOD FOR PRODUCING TRIFLUOROMETHANESULFONYLOXY COMPOUND OR TRIFLUOROMETHANESULFONYL COMPOUND AFF1, BRAF, AFF2 ACHE 3266/4885ALDH1A1 2621/4885TDP1 1156/4885
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 ACHE 3315/4885ALDH1A1 1008/4885TDP1 2058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.