Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633279 | 0.82 | LMNA (0.44) | LMNAP2RX3P2RX2NFKB1BLM | |
| SCHEMBL4046039 | 0.81 | LMNA (0.42) | LMNAP2RX3P2RX2NFKB1BLM | |
| SCHEMBL10584431 | 0.76 | ALDH1A1 (0.42) | LMNAP2RX3P2RX2NFKB1KDM4E | |
| SCHEMBL5957155 | 0.71 | P2RX3 (0.54) | LMNAP2RX3P2RX2 | |
| SCHEMBL30068211 | 0.71 | P2RX3 (0.54) | LMNAP2RX3P2RX2 | |
| SCHEMBL26647089 | 0.68 | LMNA (0.50) | LMNAP2RX3P2RX2TKTKDM4E | |
| SCHEMBL29198056 | 0.68 | LMNA (0.42) | LMNAP2RX3P2RX2TKTKDM4E | |
| SCHEMBL3618934 | 0.68 | LMNA (0.46) | LMNANFKB1KDM4EALDH1A1 | |
| SCHEMBL29234060 | 0.67 | SYK (0.36) | — | |
| SCHEMBL788493 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017772-B1 | METHOD OF IMPROVING THE SOLUBILITY OF BIOLOGICALLY ACTIVE AGENTS IN WATER AND IN LOWER ALIPHATIC ALCOHOLS, AND COMPOUNDS HAVING AN IMPROVED SOLUBILITY | BAYER AG (DE) | 1982-07-28 | — | — | EP | disclosed |
| EP-0014263-B1 | METHOD OF IMPROVING THE SOLUBILITY OF BIOLOGICALLY ACTIVE AGENTS IN WATER AND IN LOWER ALIPHATIC ALCOHOLS, AND COMPOUNDS HAVING AN IMPROVED SOLUBILITY | BAYER AG (DE) | 1982-05-05 | — | — | EP | disclosed |
| EP-0017772-A1 | Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility | BAYER AG (DE) | 1980-10-29 | — | — | EP | disclosed |
| EP-0014263-A2 | Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |