Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669905 | 0.87 | ALDH1A1 (0.58) | ALDH1A1ALDH5A1ABATVCAM1TDP1 | |
| SCHEMBL9763412 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TDP1HPRT1MAPTERN1 | |
| SCHEMBL9735773 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TDP1HPRT1MAPTHPGD | |
| SCHEMBL187061 | 0.77 | ALDH1A1 (0.63) | ALDH1A1TDP1HPRT1MAPTHPGD | |
| SCHEMBL20608200 | 0.77 | ALDH1A1 (0.63) | ALDH1A1TDP1HPRT1MAPTHPGD | |
| SCHEMBL11284187 | 0.77 | ERN1 (0.56) | ALDH1A1TDP1MAPTERN1MEN1 | |
| SCHEMBL7189950 | 0.76 | HPRT1 (0.50) | ALDH1A1ALDH5A1ABATVCAM1TDP1 | |
| SCHEMBL9734521 | 0.76 | ALDH1A1 (0.67) | ALDH1A1TDP1HPRT1MAPTHPGD | |
| SCHEMBL7836832 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TDP1HPRT1MAPTMEN1 | |
| SCHEMBL7836827 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TDP1HPRT1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086612-A1 | 9-Substituted carbacyclin analogues | THE UPJOHN COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |