SCHEMBL11212465

SCHEMBL11212465

CCN(CCC(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.43
KMT2A Q03164 5/20 0.43
MAPT P10636 4/20 0.43
MEN1 O00255 3/20 0.43
HTT P42858 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
NOX1 Q9Y5S8 2/20 0.43
GAA P10253 1/20 0.43
ELANE P08246 1/20 0.43
ALDH1A1 P00352 5/20 0.42
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TP53 P04637 1/20 0.41
PRSS1 P07477 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10909464 0.91 PRSS1 (0.46) TDP1ATML3MBTL1SMN1; SMN2KMT2A
SCHEMBL7038319 0.84 MEN1 (0.49) SMN1; SMN2KMT2AMAPTMEN1HTT
SCHEMBL8035941 0.83 SMN1; SMN2 (0.63) SMN1; SMN2KMT2AMAPTMEN1HTT
SCHEMBL9013941 0.82 KMT2A (0.45) L3MBTL1SMN1; SMN2KMT2AMAPTMEN1
SCHEMBL10782673 0.81 TDP1 (0.47) TDP1ATML3MBTL1SMN1; SMN2KMT2A
SCHEMBL27540372 0.80 SMN1; SMN2 (0.42) SMN1; SMN2KMT2AMAPTMEN1HTT
SCHEMBL8018555 0.80 KMT2A (0.54) SMN1; SMN2KMT2AMAPTMEN1HTT
SCHEMBL8543627 0.79 SMN1; SMN2 (0.41) SMN1; SMN2KMT2AMAPTMEN1HTT
SCHEMBL2069787 0.79 SMN1; SMN2 (0.41) TDP1SMN1; SMN2KMT2AMAPTMEN1
SCHEMBL11148002 0.79 ATM (0.42) TDP1ATML3MBTL1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
US-4101541-A DYES FOR POLYESTERS OR POLYPROPYLENE CIBA-GEIGY CORPORATION (US) 1978-07-18 US disclosed