SCHEMBL11148002

SCHEMBL11148002

CCN(CCOC(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SCN5A Q14524 1/20 0.42
SCN9A Q15858 1/20 0.42
SCN10A Q9Y5Y9 1/20 0.42
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
NOX1 Q9Y5S8 1/20 0.41
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11671229 0.99 SCN5A (0.44) ATMTDP1L3MBTL1SCN5ASCN9A
SCHEMBL11670465 0.92 MTNR1A (0.46) TDP1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL11671564 0.92 MAPT (0.42) SCN5ASCN9ASCN10ALMNACYP1A2
SCHEMBL11702440 0.92 NPC1 (0.44) SCN5ASCN9ASCN10ALMNACYP1A2
SCHEMBL11671985 0.92 KDM4E (0.44) ATMTDP1L3MBTL1SCN5ASCN9A
SCHEMBL11672433 0.92 ALDH1A1 (0.41) ATMTDP1L3MBTL1LMNACYP2D6
SCHEMBL11672894 0.91 TDP1 (0.47) ATMTDP1L3MBTL1SCN5ASCN9A
SCHEMBL11671579 0.91 RAB9A (0.49) L3MBTL1SCN5ASCN9ASCN10ALMNA
SCHEMBL11671037 0.91 MEN1 (0.51) L3MBTL1SCN5ASCN9ASCN10ALMNA
SCHEMBL11670563 0.90 MAOB (0.41) ATMTDP1L3MBTL1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4392998-A One pot diazotization, coupling and quaternization of aminotriazoles BAYER AKTIENGESELLSCHAFT (DE) 1983-07-12 US disclosed
US-4039526-A PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed
US-4039539-A 1,2,4-Triazole-azo-aniline cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed