Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634994 | 0.83 | NR1H4 (0.58) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1556345 | 0.83 | NAAA (0.54) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1416822 | 0.81 | NAAA (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1416655 | 0.79 | RAB9A (0.49) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| SCHEMBL4611015 | 0.76 | NPC1 (0.54) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| SCHEMBL727648 | 0.76 | RAB9A (0.53) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| SCHEMBL692327 | 0.74 | RAB9A (0.49) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| SCHEMBL18151630 | 0.74 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC8SMN1; SMN2 | |
| Benzoic Acid Hydrazide SCHEMBL11870297 | 0.74 | HDAC3 (0.60) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| Pimelic Acid SCHEMBL28874757 | 0.74 | HDAC1 (0.66) | HDAC3HDAC1HDAC7HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311704-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1982-01-19 | — | — | US | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |