SCHEMBL11213262

SCHEMBL11213262

C=C(C)C(=O)OCCOC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
LMNA P02545 3/20 0.53
MAPK1 P28482 3/20 0.53
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
ELANE P08246 1/20 0.41
THRB P10828 1/20 0.41
MAPT P10636 2/20 0.39
RAB9A P51151 2/20 0.39
XBP1 P17861 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ESR1 P03372 1/20 0.37
TSHR P16473 2/20 0.36
CYP19A1 P11511 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11408376 0.89 ALDH1A1 (0.55) ALDH1A1LMNAMAPK1TDP1MAPT
SCHEMBL11433245 0.88 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1TDP1POLB
SCHEMBL11342998 0.87 ALDH1A1 (0.58) ALDH1A1LMNAMAPK1TDP1POLB
SCHEMBL11401792 0.87 ALDH1A1 (0.49) ALDH1A1LMNAMAPK1TDP1THRB
SCHEMBL12253186 0.86 LMNA (0.55) ALDH1A1LMNAMAPK1TDP1POLB
SCHEMBL8411652 0.84 ALDH1A1 (0.54) ALDH1A1LMNAMAPK1TDP1ELANE
SCHEMBL11207543 0.84 ALDH1A1 (0.53) ALDH1A1LMNAMAPK1TDP1MAPT
SCHEMBL4743488 0.84 ALDH1A1 (0.63) ALDH1A1LMNAMAPK1TDP1POLB
SCHEMBL32669188 0.84 LMNA (0.59) ALDH1A1LMNAMAPK1TDP1MAPT
SCHEMBL8861993 0.84 TDP1 (0.47) ALDH1A1LMNAMAPK1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026339-B1 RADIATION CURABLE COATING COMPOSITION AND PROCESS FOR COATING A SUBSTRATE THEREWITH GAF CORPORATION (US) 1983-11-30 EP claimed
US-4276136-A Radiation curable coating composition comprising an ethylenically unsaturated oligomer and an ethylenically unsaturated copolymerizable ultra-violet absorber GAF CORPORATION (US) 1981-06-30 US claimed
EP-0026339-A1 Radiation curable coating composition and process for coating a substrate therewith GAF CORPORATION (US) 1981-04-08 EP claimed
US-4178303-A (2-Cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1979-12-11 US claimed
WO-2022255228-A1 COMPOSITION, CURED PRODUCT OR COMPACT, OPTICAL MEMBER, AND LENS 富士フイルム株式会社 2022-12-08 WO disclosed
US-4218392-A Two-step method of making copolymerizable, ultraviolet light absorber _2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-08-19 US disclosed
US-4207253-A Method of making copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1980-06-10 US disclosed
US-4178303-A (2-Cyano-3,3-diphenylacryloxy) alkylene acrylic acid esters GAF CORPORATION (US) 1979-12-11 US disclosed