SCHEMBL11401792

SCHEMBL11401792

C=C(C)COCCOC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MAPK1 P28482 3/20 0.49
LMNA P02545 3/20 0.49
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 3/20 0.36
RAB9A P51151 2/20 0.36
XBP1 P17861 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ESR1 P03372 1/20 0.34
THRB P10828 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8411652 0.88 ALDH1A1 (0.54) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL11213262 0.87 ALDH1A1 (0.53) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL16486985 0.84 ALDH1A1 (0.56) ALDH1A1MAPK1LMNASMN1; SMN2MAPT
SCHEMBL11408376 0.84 ALDH1A1 (0.55) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL10135989 0.83 LMNA (0.52) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL12253191 0.83 ALDH1A1 (0.58) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL12253186 0.81 LMNA (0.55) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL28097992 0.81 MAPK1 (0.50) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL11421380 0.81 ALDH1A1 (0.47) ALDH1A1MAPK1LMNATDP1SMN1; SMN2
SCHEMBL11208690 0.81 ALDH1A1 (0.47) ALDH1A1MAPK1LMNATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4263366-A Radiation curable coating composition comprising an oligomer and a copolymerizable ultra-violet absorber GAF CORPORATION (US) 1981-04-21 US claimed
US-4202834-A Copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene ethylenic ethers GAF CORPORATION (US) 1980-05-13 US claimed
EP-0017703-A1 Copolymerizable (2-cyano-3,3-diarylacryloxy)alkylene compounds, a method of making them and the use of these compounds as ultraviolet light absorbers GAF CORPORATION (US) 1980-10-29 EP disclosed
US-4202834-A Copolymerizable, ultraviolet light absorber (2-cyano-3,3-diphenylacryloxy) alkylene ethylenic ethers GAF CORPORATION (US) 1980-05-13 US disclosed