Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | EPOR | P19235 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213363 | 1.00 | ALOX5 (0.46) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL4109907 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL867262 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL867263 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL4109909 | 0.81 | ALDH1A1 (0.44) | LMNAALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11172012 | 0.79 | ATM (0.53) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL11172009 | 0.79 | ATM (0.53) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL11155936 | 0.78 | ATM (0.54) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL9810862 | 0.76 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL9810865 | 0.76 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALOX5APATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370277-A | Phenoxy-cinnamyl alcohols | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-25 | — | — | US | disclosed |