Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EPOR | P19235 | 2/20 | 0.46 |
| ▸ | TLR4 | O00206 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810865 | 1.00 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL11183385 | 0.88 | ALOX5 (0.40) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL9810874 | 0.86 | ALOX5 (0.49) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL9810873 | 0.86 | ALOX5 (0.49) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL9810847 | 0.83 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL11155936 | 0.83 | ATM (0.54) | ALOX5PTGS1PTGS2ALOX5APATM | |
| SCHEMBL5078610 | 0.78 | TSHR (0.50) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL295402 | 0.78 | TSHR (0.50) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL295401 | 0.78 | TSHR (0.50) | MEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL11176166 | 0.77 | ALDH1A1 (0.62) | ALOX5PTGS1PTGS2ALOX5APATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262870-B1 | MORPHOLINE, PIPERIDINE AND TETRAHYDROPYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-4837236-A | CONTROLLING PHYTOPATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0262870-A2 | Morpholine, piperidine and tetrahydropyridine derivatives, processes for their preparation and their use as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-04-06 | — | — | EP | disclosed |