SCHEMBL11213567

CC1(C)CC(OC(=O)Cn2c(=O)n(CC(=O)OC3CC(C)(C)N(Cc4ccccc4)C(C)(C)C3)c(=O)n(CC(=O)OC3CC(C)(C)N(Cc4ccccc4)C(C)(C)C3)c2=O)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	5/20	0.40

▸	TSHR	P16473	3/20	0.40

▸	GAA	P10253	4/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	HTT	P42858	1/20	0.39

▸	MEN1	O00255	3/20	0.39

▸	ALDH1A1	P00352	1/20	0.37

▸	AMPD2	Q01433	1/20	0.36

▸	MAPT	P10636	2/20	0.36

▸	CTDSP1	Q9GZU7	1/20	0.36

▸	KDM4E	B2RXH2	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11217915	0.88	KMT2A (0.41)	KMT2ATSHRGAAHTTMEN1
SCHEMBL11403013	0.86	TSHR (0.44)	KMT2ATSHRGAAHTTMEN1
SCHEMBL9243231	0.82	KMT2A (0.43)	KMT2ATSHRGAAHTTMEN1
SCHEMBL315331	0.80	TSHR (0.43)	KMT2ATSHRGAAHTTMEN1
SCHEMBL315332	0.80	TSHR (0.43)	KMT2ATSHRGAAHTTMEN1
SCHEMBL14556856	0.79	TSHR (0.39)	KMT2ATSHRGAAHTTMEN1
SCHEMBL27501250	0.79	CYP2D6 (0.42)	KMT2ATSHRGAAHTTMEN1
SCHEMBL11179317	0.79	CHRM3 (0.43)	KMT2ATSHRGAAHTTMEN1
SCHEMBL11259423	0.78	GAA (0.43)	KMT2ATSHRGAAHTTMEN1
SCHEMBL9229439	0.78	TSHR (0.47)	KMT2ATSHRGAAHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4317911-A	LIGHT STABILIZERS FOR POLYMERS	CIBA-GEIGY CORPORATION (US)	1982-03-02	—	—	US	disclosed