SCHEMBL9243231

SCHEMBL9243231

CC1(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(Cc3ccccc3)C(C)(C)C2)CC(C)(C)N1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
GAA P10253 3/20 0.43
MEN1 O00255 2/20 0.43
TSHR P16473 3/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
AMPD2 Q01433 2/20 0.38
EPHX2 P34913 1/20 0.38
NAAA Q02083 2/20 0.38
HPGD P15428 1/20 0.38
ABL1 P00519 1/20 0.36
RIN1 Q13671 1/20 0.36
NR1H2 P55055 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11403013 0.88 TSHR (0.44) KMT2AGAAMEN1TSHRHTT
SCHEMBL11217915 0.85 KMT2A (0.41) KMT2AGAAMEN1TSHRHTT
SCHEMBL13246445 0.83 GAA (0.39) KMT2AGAAMEN1TSHRHTT
SCHEMBL698553 0.82 KMT2A (0.47) KMT2AGAAMEN1TSHRHTT
SCHEMBL11213567 0.82 KMT2A (0.40) KMT2AGAAMEN1TSHRHTT
SCHEMBL315332 0.82 TSHR (0.43) KMT2AGAAMEN1TSHRHTT
SCHEMBL315331 0.82 TSHR (0.43) KMT2AGAAMEN1TSHRHTT
SCHEMBL8378344 0.81 L3MBTL1 (0.39) KMT2AGAAMEN1TSHRHTT
SCHEMBL8517226 0.81 L3MBTL1 (0.39) KMT2AGAAMEN1TSHRHTT
SCHEMBL14556856 0.81 TSHR (0.39) KMT2AGAAMEN1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0237485-B1 Stabilized compositions of rigid PVC CIBA GEIGY AG (CH) 1995-01-18 EP claimed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
EP-0257321-B1 IMPROVING WEATHERABILITY AND ADHERENCE OF POLYPROPYLENE ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-03-13 EP disclosed
US-4997888-A Tetramethyl piperidyl compound ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-03-05 US disclosed
US-4994529-A Surface activation with oxygen; piperidyl stabilizer and phenolic antioxidant present ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-02-19 US disclosed
EP-0257321-A2 Improving weatherability and adherence of polypropylene ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-03-02 EP disclosed
US-4314933-A 2,2,6,6-TETRAALKYLPIPERIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed
US-4284485-A STABILIZED WITH A POLYALKYLPIPERIDINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed