Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520882 | 0.82 | HSD17B10 (0.52) | KIF11HTTCYP2C9CYP2D6HIF1A | |
| SCHEMBL14152516 | 0.82 | ADRB2 (0.48) | HTTCYP2C9CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL16750532 | 0.82 | ALOX5 (0.50) | KIF11EPHX1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL951315 | 0.82 | ADRB2 (0.48) | HTTCYP2C9CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL987111 | 0.82 | ALOX5 (0.50) | KIF11EPHX1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11213779 | 0.80 | KIF11 (0.43) | KIF11HTTCYP2C9CYP2D6HIF1A | |
| Bromide SCHEMBL10989191 | 0.80 | ADRB2 (0.46) | HTTCYP2C9CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL1354755 | 0.79 | ESR1 (0.42) | HTTCYP2C9CYP2D6HIF1ATYR | |
| SCHEMBL1354759 | 0.79 | ESR1 (0.42) | HTTCYP2C9CYP2D6HIF1ATYR | |
| SCHEMBL12406374 | 0.79 | ESR1 (0.42) | HTTCYP2C9CYP2D6HIF1ATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |