Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461511 | 0.88 | SREBF2 (0.65) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL11213832 | 0.87 | RAB9A (0.77) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL25959093 | 0.83 | MPL (0.57) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL23016100 | 0.82 | CYP17A1 (0.55) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL11455579 | 0.80 | SREBF2 (0.59) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL1206993 | 0.79 | RAB9A (0.66) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL17336572 | 0.79 | RAB9A (0.66) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL13379242 | 0.79 | RAB9A (1.00) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL2781370 | 0.79 | KDM4E (0.85) | RAB9ASMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL8698425 | 0.78 | ATP4A (0.57) | RAB9AMAPTNPC1KDM4EATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153703-A | Method of controlling insects and acarids with certain aryl-substituted thiazoles | UNIROYAL, INC. (US) | 1979-05-08 | — | — | US | disclosed |