Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849495 | 0.86 | CA1 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4958909 | 0.78 | CA12 (0.61) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27869030 | 0.78 | ALDH1A1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL22589590 | 0.77 | CYP1A2 (0.42) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7809866 | 0.77 | TSHR (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8716306 | 0.77 | ALDH1A1 (0.43) | CA1CA2CA12CA7CA9 | |
| SCHEMBL25264151 | 0.74 | FOLH1 (0.49) | GAAKDM4ENOTUM | |
| SCHEMBL31212991 | 0.74 | FOLH1 (0.49) | GAAKDM4ENOTUM | |
| Nitrous Acid SCHEMBL28878891 | 0.73 | NOTUM (0.39) | CA1CA2CA12CA7CA9 | |
| SCHEMBL22890667 | 0.72 | LRRK2 (0.47) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090603-A2 | Antibacterial compounds | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |