Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215571 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL10821368 | 0.78 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1LMNATP53KDM4E | |
| SCHEMBL11214313 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL11162712 | 0.74 | KMT2A (0.43) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL11216906 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL11169766 | 0.71 | MAPT (0.52) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL11215371 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ACYP1A2NPC1 | |
| SCHEMBL11398951 | 0.69 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11294057 | 0.68 | KMT2A (0.41) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21518221 | 0.68 | FFAR2 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314842-A | Herbicidal substituted 1,3,4-thiadiazol-2-yl-4-hydroxy-1-methyl-2-imidazolidinones | PPG INDUSTRIES, INC. (US) | 1982-02-09 | — | — | US | disclosed |