Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671600 | 0.81 | RAB9A (0.48) | RAB9AMAPTNPC1TDP1MAOB | |
| SCHEMBL6667533 | 0.81 | PPARG (0.52) | RAB9AMAPTNPC1MAOBMAPK1 | |
| SCHEMBL9750011 | 0.81 | CA12 (0.62) | RAB9AMAPTNPC1MAOBMAPK1 | |
| SCHEMBL3628980 | 0.80 | ESR1 (0.61) | RAB9AMAPTNPC1TDP1MAOB | |
| SCHEMBL471706 | 0.80 | PPARG (0.61) | RAB9AMAPTNPC1TDP1MAOB | |
| SCHEMBL9329226 | 0.79 | MAOB (0.68) | RAB9AMAPTNPC1TDP1MAOB | |
| SCHEMBL3256021 | 0.78 | CA12 (0.61) | RAB9ASMN1; SMN2KMT2ATSHRKDM4E | |
| SCHEMBL6394260 | 0.77 | ESR1 (0.56) | RAB9AMAPTNPC1TDP1MAOB | |
| SCHEMBL20831010 | 0.75 | KMT2A (0.58) | RAB9AMAPTNPC1TDP1MAPK1 | |
| SCHEMBL20831007 | 0.75 | TDP1 (0.58) | RAB9AMAPTNPC1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4401603-A | CHLORINATION OF THE SOLUTION OR SUSPENSION FORMED BY THE FORMYLATION OF AN ARYLAMINE IN A SOLVENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |