SCHEMBL471706

SCHEMBL471706

Cc1ccccc1COC(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.61
TDP1 Q9NUW8 2/20 0.59
KMT2A Q03164 2/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A3 Q01959 1/20 0.59
ALDH1A1 P00352 4/20 0.53
MAPT P10636 4/20 0.53
MAOB P27338 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ADORA2A P29274 1/20 0.53
LMNA P02545 2/20 0.53
HPGD P15428 2/20 0.51
RAB9A P51151 3/20 0.50
MAPK1 P28482 2/20 0.50
HIF1A Q16665 1/20 0.50
NPC1 O15118 1/20 0.50
TSHR P16473 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628980 0.90 ESR1 (0.61) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL9329226 0.88 MAOB (0.68) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL5085480 0.87 PPARG (0.71) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL6394260 0.85 ESR1 (0.56) PPARGTDP1KMT2ASLC6A2ALDH1A1
SCHEMBL28956479 0.84 PPARG (0.56) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL9190522 0.83 MAOB (0.51) KMT2AALDH1A1MAPTMAOBKDM4E
SCHEMBL14937718 0.83 TDP1 (0.65) TDP1KMT2AALDH1A1MAPTKDM4E
SCHEMBL9329029 0.83 MAOB (0.47) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL16673146 0.83 LMNA (0.59) PPARGTDP1KMT2ASLC6A2SLC6A3
SCHEMBL9578209 0.82 L3MBTL1 (0.58) TDP1KMT2AALDH1A1MAPTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119584860-A Comprising biodegradable microcapsule composition 奇华顿股份有限公司 2025-03-07 CN disclosed
US-20240374492-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2024-11-14 US disclosed
CN-118771982-A Method for improving yield of aldol resin in process of producing methylbenzoic acid based on dimethylbenzene oxidation 阿拉善左旗旻利化工有限责任公司 2024-10-15 CN disclosed
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) 2024-01-18 US disclosed
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) 2024-01-18 US disclosed
US-20230015617-A1 PHTHALAZINONE DERIVATIVES KUDOS PHARMACEUTICALS LIMITED (GB) 2023-01-19 US disclosed
US-11160803-B2 Phthalazinone derivatives KUDOS PHARMACEUTICALS LIMITED (GB) 2021-11-02 US disclosed
EP-3883647-A1 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF Zikani Therapeutics, Inc. (US) 2021-09-29 EP disclosed
CN-106458827-B Process for purifying benzoic acid 苏尔寿管理有限公司 2021-07-09 CN disclosed
CN-110845327-A Process for purifying benzoic acid 苏舍化学技术有限公司 2020-02-28 CN disclosed
EP-2390245-A1 Enantiomerically pure amines Nabriva Therapeutics AG (AT) 2011-11-30 EP disclosed
US-8022072-B2 Azolylmethylidenehydrazine derivative and use thereof KAKEN PHARMACEUTICAL CO., LTD. (JP) 2011-09-20 US disclosed
US-7993732-B2 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2011-08-09 US disclosed
US-7795261-B2 Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists JANSSEN PHARMACEUTICA NV (BE) 2010-09-14 US disclosed
US-20100190754-A1 AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF KAKEN PHARMACEUTICAL CO., LTD. (JP) 2010-07-29 US disclosed
US-7572786-B2 Irritable bowel syndrome; tachykinin mediated condition such as schizophrenia, emesis, anxiety, depression, irritable bowel syndrome, circadian rhythm disturbances, pain, neurogenic inflammation, asthma, micturition disorder or nociception JANSSEN PHARMACEUTICA, N.V. (BE) 2009-08-11 US disclosed
US-20080026205-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material RICOH COMPANY, LTD. (JP) 2008-01-31 US disclosed
EP-1882726-A1 Heat-sensitive pressure-sensitive adhesive and heat-sensitive adhesive material Ricoh Company, Ltd. (JP) 2008-01-30 EP disclosed
WO-2004080976-A1 PHTHALAZINONE DERIVATIVES KUDOS PHARMACEUTICALS LIMITED (GB) 2004-09-23 WO disclosed
US-4387243-A Continuous production of ortho-phthalic acid product by two-step catalytic neat oxidation of liquid ortho-xylene with air STANDARD OIL COMPANY (INDIANA) (US) 1983-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160803-B2 Phthalazinone derivatives NR0B1, NR0B2, NR2E1 PPARG 523/4885TDP1 3363/4885KMT2A 2203/4885
US-20240016775-A1 ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR PARP3, PARP1, PARP4 PPARG 4280/4885TDP1 288/4885KMT2A 2392/4885
US-20230015617-A1 PHTHALAZINONE DERIVATIVES NR0B1, NR0B2, NR2E1 PPARG 481/4885TDP1 3392/4885KMT2A 2142/4885
US-20100190754-A1 AZOLYLMETHYLIDENEHYDRAZINE DERIVATIVE AND USE THEREOF ARSA, AHR, HRH2 PPARG 1727/4885TDP1 4865/4885KMT2A 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.