SCHEMBL6667533

SCHEMBL6667533

Cc1ccccc1COC(=O)c1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.52
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
MAOB P27338 1/20 0.51
MAPT P10636 3/20 0.51
HRH3 Q9Y5N1 2/20 0.50
KDM4E B2RXH2 4/20 0.49
RXFP1 Q9HBX9 3/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
ATM Q13315 1/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
HPGD P15428 1/20 0.49
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
ADRB3 P13945 1/20 0.49
DRD3 P35462 1/20 0.48
HTT P42858 1/20 0.47
DRD4 P21917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750011 0.82 CA12 (0.62) NPC1RAB9AMAOBMAPTKDM4E
SCHEMBL6671600 0.82 RAB9A (0.48) PPARGNPC1RAB9AMAOBMAPT
SCHEMBL3628980 0.81 ESR1 (0.61) PPARGNPC1RAB9AMAOBMAPT
SCHEMBL11214224 0.81 RAB9A (0.50) NPC1RAB9AMAOBMAPTKDM4E
SCHEMBL30684671 0.81 CA12 (0.59) NPC1RAB9AMAPTHRH3KDM4E
SCHEMBL571295 0.81 CA12 (0.59) NPC1RAB9AMAPTHRH3KDM4E
SCHEMBL471706 0.81 PPARG (0.61) PPARGNPC1RAB9AMAOBMAPT
SCHEMBL9329226 0.80 MAOB (0.68) PPARGNPC1RAB9AMAOBMAPT
SCHEMBL14783221 0.80 CYBB (0.67) PPARGNPC1RAB9AMAPTHRH3
Hydrochloric Acid SCHEMBL27804731 0.80 CA12 (0.57) NPC1RAB9AMAPTHRH3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed