Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358069 | 0.85 | ADRB2 (0.76) | ADRB2ADRB1ADRB3MEN1LMNA | |
| SCHEMBL2615175 | 0.83 | ADRB1 (0.70) | ADRB2ADRB1ADRB3MEN1LMNA | |
| SCHEMBL10795367 | 0.82 | ADRB1 (0.60) | ADRB2ADRB1ADRB3MEN1LMNA | |
| Hydrochloric Acid SCHEMBL10791509 | 0.81 | ADRB1 (0.58) | ADRB2ADRB1ADRB3MEN1LMNA | |
| SCHEMBL11848235 | 0.76 | ADRB2 (0.56) | ADRB2ADRB1 | |
| SCHEMBL20552995 | 0.75 | ADRB1 (0.66) | ADRB2ADRB1ADRB3 | |
| SCHEMBL22640035 | 0.75 | KMT2A (0.68) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL22640064 | 0.75 | KMT2A (0.68) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11854665 | 0.74 | ADRB2 (1.00) | ADRB2ADRB1ADRB3LMNANFKB1 | |
| SCHEMBL13204416 | 0.74 | ADRB1 (0.78) | ADRB2ADRB1ADRB3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068160-A1 | Use of 1-(p-Isopropoxyethoxymethyl-phenoxy)-3-isopropylaminopropan-2-ol for the preparation of a medicament for the reduction of internal pressure in the eye | MERCK PATENT GmbH (DE) | 1983-01-05 | — | — | EP | claimed |