Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.70 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284536 | 0.88 | ADRB2 (0.69) | ADRB1ADRB2ADRB3MEN1LMNA | |
| SCHEMBL11214232 | 0.83 | ADRB2 (0.58) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL20960 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL233810 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL20961 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL6510329 | 0.82 | ADRB1 (1.00) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL4269272 | 0.81 | ADRB1 (0.98) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL3137111 | 0.81 | ADRB2 (0.98) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL16821829 | 0.81 | ADRB1 (0.98) | ADRB1ADRB2ADRB3MEN1LMNA | |
| Bisoprolol SCHEMBL3137123 | 0.81 | ADRB2 (0.98) | ADRB1ADRB2ADRB3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | ADRB1 4715/4885ADRB2 4657/4885ADRB3 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.