SCHEMBL11214715

SCHEMBL11214715

[NH]C(=O)COc1ccccc1CN

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 3/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.41
CFD P00746 1/20 0.40
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40
F11 P03951 1/20 0.40
KLKB1 P03952 1/20 0.40
F7 P08709 1/20 0.40
TPSB2 P20231 1/20 0.40
POLB P06746 2/20 0.40
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TBXAS1 P24557 2/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.38
NPY1R P25929 1/20 0.38
NPY2R P49146 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6975532 0.85 HTT (0.61) L3MBTL1KDM4EHTTSMN1; SMN2CFD
SCHEMBL4837994 0.84 L3MBTL1 (0.65) L3MBTL1KDM4EHTTSMN1; SMN2CFD
SCHEMBL8714203 0.79 SMN1; SMN2 (0.53) L3MBTL1HTTSMN1; SMN2TSHRHPGD
SCHEMBL10969595 0.78 ALDH1A1 (0.52) L3MBTL1KDM4EHTTSMN1; SMN2POLB
SCHEMBL4185732 0.76 NPSR1 (0.54) L3MBTL1HTTSMN1; SMN2POLBTSHR
SCHEMBL10971331 0.76 GAA (0.56) L3MBTL1SMN1; SMN2POLBGLATSHR
SCHEMBL16106140 0.74 PNMT (0.44) L3MBTL1KDM4ESMN1; SMN2CFDPLG
SCHEMBL9201385 0.74 GRM4 (0.58) L3MBTL1KDM4EHTTSMN1; SMN2ALDH1A1
SCHEMBL10968374 0.74 NOTUM (0.58) L3MBTL1HTTSMN1; SMN2POLBTSHR
SCHEMBL11212899 0.74 HPGD (0.55) L3MBTL1KDM4EHTTSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4329454-A Cephalosporin compounds ELI LILLY AND COMPANY (US) 1982-05-11 US disclosed