Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 15/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212569 | 0.79 | BCHE (0.42) | BCHE | |
| Hydrochloric Acid SCHEMBL9791968 | 0.78 | HTR2C (0.48) | — | |
| SCHEMBL22703437 | 0.70 | DRD3 (0.62) | — | |
| SCHEMBL22694040 | 0.70 | DRD3 (0.62) | — | |
| SCHEMBL7272088 | 0.70 | FABP4 (0.43) | — | |
| Hydrochloric Acid SCHEMBL7281139 | 0.68 | SLC2A1 (0.47) | BCHE | |
| SCHEMBL11214217 | 0.66 | ADRA2A (0.76) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7281304 | 0.66 | TAAR1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL11215555 | 0.65 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL6215213 | 0.65 | MAPT (0.67) | BCHEADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043194-A2 | Bicyclo-octatriene derivatives, pharmaceutical compositions containing them and processes and intermediates for their production | FISONS plc (GB) | 1982-01-06 | — | — | EP | claimed |