Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215369 | 1.00 | MAOB (0.58) | MAOBABCG2CYP1A1CYP1B1FAAH | |
| SCHEMBL11219001 | 0.91 | FAAH (0.57) | MAOBABCG2FAAHMEN1KMT2A | |
| SCHEMBL11219002 | 0.91 | FAAH (0.57) | MAOBABCG2FAAHMEN1KMT2A | |
| SCHEMBL28536397 | 0.85 | HSD11B1 (0.62) | MAOBMEN1KMT2APOLBLMNA | |
| SCHEMBL19244469 | 0.82 | ABCG2 (0.62) | MAOBABCG2CYP1A1CYP1B1NPC1 | |
| SCHEMBL19244225 | 0.82 | APP (0.62) | ABCG2CYP1A1CYP1B1NPC1RAB9A | |
| SCHEMBL15969787 | 0.82 | KMT2A (0.60) | ABCG2FAAHNPC1RAB9AKMT2A | |
| SCHEMBL9478186 | 0.82 | MEN1 (0.71) | MAOBABCG2CYP1A1CYP1B1NPC1 | |
| SCHEMBL9478189 | 0.82 | MEN1 (0.71) | MAOBABCG2CYP1A1CYP1B1NPC1 | |
| SCHEMBL19244313 | 0.81 | CA12 (0.65) | MAOBABCG2CYP1A1CYP1B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57081440-A | — | — | None | — | — | JP | disclosed |
| JP-S5781440-A | 4-FLUOROPHENOL CINNAMIC ACID ESTER DERIVATIVE | CHISSO CORP | 1982-05-21 | — | — | JP | disclosed |