Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545557 | 0.93 | CA12 (0.57) | HSD11B1KMT2AMEN1TNFRSF1AKDM4E | |
| SCHEMBL28542113 | 0.92 | KMT2A (0.57) | HSD11B1KMT2AMEN1TNFRSF1AKDM4E | |
| SCHEMBL27737751 | 0.92 | KMT2A (0.54) | HSD11B1KMT2AMEN1TNFRSF1AKDM4E | |
| SCHEMBL28541241 | 0.89 | CYP2D6 (0.52) | HSD11B1KMT2AMEN1TNFRSF1AKDM4E | |
| SCHEMBL27758520 | 0.86 | MAOB (0.66) | KMT2AMEN1MAPTMAOBLMNA | |
| SCHEMBL28894377 | 0.86 | KMT2A (0.48) | HSD11B1KMT2AMEN1TNFRSF1AKDM4E | |
| SCHEMBL11215369 | 0.85 | MAOB (0.58) | KMT2AMEN1KDM4EGAAPOLB | |
| SCHEMBL11215372 | 0.85 | MAOB (0.58) | KMT2AMEN1KDM4EGAAPOLB | |
| SCHEMBL21848007 | 0.84 | HSD11B1 (0.67) | HSD11B1KMT2AMEN1TNFRSF1APOLB | |
| SCHEMBL776127 | 0.84 | HSD11B1 (0.67) | HSD11B1KMT2AMEN1TNFRSF1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112624927-B | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-112691099-B | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-112691099-A | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-112624927-A | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2021-04-09 | — | — | CN | disclosed |