Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850918 | 1.00 | SIGMAR1 (0.38) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11215377 | 1.00 | SIGMAR1 (0.38) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11707488 | 0.86 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10534035 | 0.76 | GRM5 (0.36) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL11845472 | 0.76 | GRM5 (0.36) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL11157322 | 0.70 | SMN1; SMN2 (0.37) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL11157294 | 0.70 | SMN1; SMN2 (0.37) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL297319 | 0.69 | MEN1 (0.54) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4434862 | 0.69 | ATM (0.45) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12889079 | 0.69 | SIGMAR1 (0.54) | SIGMAR1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027197-B1 | PROCESS FOR THE PRODUCTION OF ADDITION COMPOUNDS FROM CARBODIIMIDES AND COMPOUNDS CONTAINING HYDROXYL GROUPS | BAYER AG (DE) | 1982-08-25 | — | — | EP | disclosed |
| EP-0027197-A1 | Process for the production of addition compounds from carbodiimides and compounds containing hydroxyl groups | BAYER AG (DE) | 1981-04-22 | — | — | EP | disclosed |