Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867460 | 0.82 | GNAI3 (0.43) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL5831370 | 0.81 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HDAC3HDAC8 | |
| SCHEMBL28088423 | 0.81 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HDAC3HDAC8 | |
| SCHEMBL27952331 | 0.81 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HDAC3HDAC8 | |
| SCHEMBL28088710 | 0.81 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HDAC3HDAC8 | |
| SCHEMBL28088485 | 0.81 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HDAC3HDAC8 | |
| SCHEMBL28006589 | 0.81 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HDAC3HDAC8 | |
| SCHEMBL11665961 | 0.68 | ALDH1A1 (0.43) | GNAI3GNAO1GNAI1ALDH1A1TSHR | |
| SCHEMBL6072900 | 0.67 | NPC1 (0.43) | ALDH1A1 | |
| SCHEMBL28145460 | 0.67 | ALDH1A1 (0.42) | GNAI3GNAO1GNAI1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073960-A1 | 2-Arylhydrazino-2-imidazolines, their acyl derivatives, process for their preparation and their use in the control of endoparasites and ectoparasites | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0073960-A1 | 2-Arylhydrazino-2-imidazolines, their acyl derivatives, process for their preparation and their use in the control of endoparasites and ectoparasites | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |
| EP-0073394-A1 | 2-Arylazo-2-imidazolines, acyl derivatives of the same, process for their preparation and the use in the control of ectoparasites and/or endoparasites | BAYER AG (DE) | 1983-03-09 | — | — | EP | disclosed |