Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810537 | 0.87 | CYP4F2 (0.44) | TBXAS1ALDH1A1MAPTCYP4F2CYP4A11 | |
| SCHEMBL10753712 | 0.87 | CYP4F2 (0.44) | TBXAS1ALDH1A1MAPTCYP4F2CYP4A11 | |
| SCHEMBL9496265 | 0.87 | CYP4F2 (0.44) | TBXAS1ALDH1A1MAPTCYP4F2CYP4A11 | |
| SCHEMBL11808317 | 0.87 | CYP4F2 (0.44) | TBXAS1ALDH1A1MAPTCYP4F2CYP4A11 | |
| SCHEMBL9498988 | 0.87 | CYP4F2 (0.44) | TBXAS1ALDH1A1MAPTCYP4F2CYP4A11 | |
| SCHEMBL11808352 | 0.81 | CYP1A2 (0.40) | TBXAS1ALDH1A1MAPTHPGDCYP4F2 | |
| SCHEMBL2677059 | 0.79 | HPGD (0.41) | ALDH1A1HPGDLMNATDP1GAA | |
| SCHEMBL2720980 | 0.79 | HPGD (0.41) | ALDH1A1HPGDLMNATDP1GAA | |
| SCHEMBL11787951 | 0.79 | HPGD (0.41) | ALDH1A1HPGDLMNATDP1GAA | |
| SCHEMBL4967427 | 0.79 | HPGD (0.41) | ALDH1A1HPGDLMNATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338252-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4283550-A | BRONCHODILATOR AGENTS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID (US) | 1981-08-11 | — | — | US | disclosed |
| US-4267361-A | HYPOTENSIVE, ANTIULCER, AND BRONCHODILATOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| US-4260805-A | BRONCHODILATOR AGENTS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4254275-A | BRONCHODILATORS, ANTIULCER, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254278-A | BRONCHODILATORS, ANTIULCER, HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4250321-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4250323-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-02-10 | — | — | US | disclosed |