Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720980 | 1.00 | HPGD (0.41) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL11787951 | 1.00 | HPGD (0.41) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL2677059 | 1.00 | HPGD (0.41) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL9497174 | 0.99 | TSHR (0.40) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL9496137 | 0.99 | TSHR (0.40) | HPGDPTGER2TSHRLMNAALDH1A1 | |
| SCHEMBL10753712 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL9498988 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL11810537 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL9496265 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL11808317 | 0.86 | CYP4F2 (0.44) | TSHRALDH1A1GAAKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5041998-A | — | — | None | — | — | JP | disclosed |
| WO-2019011668-A1 | PROCESS FOR THE PREPARATION AND PURIFICATION OF MISOPROSTOL | CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIVATE CO. LTD. (HU) | 2019-01-17 | — | — | WO | disclosed |
| EP-0845534-B1 | Esterase gene and its use | SUMITOMO CHEMICAL CO (JP) | 2008-06-25 | — | — | EP | disclosed |
| US-6960460-B2 | Nucleotide sequences coding enzymatic polypeptide for use in the generation insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-11-01 | — | — | US | disclosed |
| US-6087145-A | CODES FOR ENZYME CAPABLE OF ASYMMETRIC HYDROLYSIS OF ORGANIC CARBOXYLIC ACID ESTER OF A CYCLOPENTENOLONE; FOR RECOMBINANT PRODUCTION OF ENZYME TO PRODUCE OPTICALLY ACTIVE CHEMICAL INTERMEDIATES OF DRUGS AND AGRICULTURAL CHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-07-11 | — | — | US | disclosed |
| EP-0845534-A2 | Esterase gene and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0357009-B1 | Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents | SEARLE & CO (US) | 1994-03-02 | — | — | EP | disclosed |
| JP-H0541998-A | PRODUCTION OF OPTICALLY ACTIVE CYCLOPENTENONE DERIVATIVE AND OPTICALLY ACTIVE CYCLOPENTENONE ESTERS | SUMITOMO CHEM CO LTD | 1993-02-23 | — | — | JP | disclosed |
| US-5106750-A | Enzymatic resolution of hydroxycyclopentenones using lipase | G. D. SEARLE & CO. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0357009-A2 | Method of resolution of hydroxy-cyclopentenones using a lipase and transacylation agents | G.D. Searle & Co. (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4245121-A | HAVING A TERMINAL CYCLIC MOIETY IN THE B-CHAIN | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4243817-A | TERMINAL CYCLIC MOIETY IN THE B-CHAIN; PROSTOGLANDIN ACTIVITY | AMERICAN CYANAMID COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4202988-A | Prostenoic acids and esters | AMERICAN CYANAMID COMPANY (US) | 1980-05-13 | — | — | US | disclosed |
| US-4197407-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |
| US-4178456-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4178461-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4060691-A | 7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters | G. D. SEARLE & CO. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3970683-A | 11,15-Dihydroxy-9-oxoprost-13-ynoic acid | G. D. SEARLE & CO. (US) | 1976-07-20 | — | — | US | disclosed |
| US-3965143-A | 16-Oxygenated prostanoic acid derivatives | G. D. SEARLE & CO. (US) | 1976-06-22 | — | — | US | disclosed |
| JP-H00541998-A | — | — | 0001-01-01 | — | — | JP | disclosed |