SCHEMBL9496265

SCHEMBL9496265

CCOC(=O)CCCCCCC1=CC(O)CC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.44
CYP4A11 Q02928 2/20 0.44
TBXAS1 P24557 1/20 0.44
ALDH1A1 P00352 3/20 0.42
ALOX15 P16050 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
USP2 O75604 1/20 0.42
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP4Z1 Q86W10 1/20 0.38
DGKA P23743 1/20 0.38
CYP1A2 P05177 1/20 0.38
NAMPT P43490 1/20 0.38
BRD4 O60885 1/20 0.38
GAA P10253 1/20 0.37
AMPD2 Q01433 2/20 0.36
EPHX2 P34913 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9498988 1.00 CYP4F2 (0.44) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL11810537 1.00 CYP4F2 (0.44) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL11808317 1.00 CYP4F2 (0.44) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL10753712 1.00 CYP4F2 (0.44) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL11808352 0.94 CYP1A2 (0.40) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL6651582 0.88 DGKA (0.49) ALDH1A1TDP1DGKAEPHX2MAPT
SCHEMBL11215706 0.87 FAAH (0.42) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL11107267 0.86 CYP4F2 (0.44) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL11554469 0.86 CYP4F2 (0.44) CYP4F2CYP4A11TBXAS1ALDH1A1ALOX15
SCHEMBL11787951 0.86 HPGD (0.41) ALDH1A1TDP1TSHRGAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4031129-A LITHIUM CYCLOPENTADIENE, ETHYL-7-BROMOHEPTANOATE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1977-06-21 US claimed
EP-0247620-B1 PRODUCTION OF CYCLOPENTENONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
US-4957867-A Production of cyclopentenones by enzyme resolution SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-18 US disclosed
EP-0247620-A2 Production of cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-02 EP disclosed
US-4703127-A Process for the preparation of prostanoids THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1987-10-27 US disclosed
US-4439365-A TRIPHENYLMETHOXY ALKENYLMAGNESIUM HALIDES AMERICAN CYANAMID COMPANY (US) 1984-03-27 US disclosed
US-4367340-A 4-Oxy-cyclopent-2-en-1-one derivative, a prostaglandin intermediate, and the process for its preparation THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1983-01-04 US disclosed
EP-0010761-B1 PROCESS FOR PREPARING 4-HYDROXY-2-CYCLOPENTEN-I-ONES, 2-METHYL-2,5-DIMETHOXY-2,5-DIHYDROFURANS AND A PROCESS FOR THEIR PREPARATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-10-13 EP disclosed
US-4343949-A PROSTAGLANDIN REARRANGEMENTS AMERICAN CYANAMID COMPANY (US) 1982-08-10 US disclosed
US-4282372-A Process for producing cyclopentenolones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-04 US disclosed
US-4076947-A BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS AMERICAN CYANAMID COMPANY (US) 1978-02-28 US disclosed
US-4061672-A Derivatives of 9-hydroxy-13-trans-prostenoic acid AMERICAN CYANAMID COMPANY (US) 1977-12-06 US disclosed
US-4060540-A BRONCHODILATORS, HYPOTENSIVE, ANTIULCER AMERICAN CYANAMID COMPANY (US) 1977-11-29 US disclosed
US-RE29469-E PROSTAGLANDINS; BRONCHODILATORS, HYPOTENSIVES, ANTIULCER AGENTS AMERICAN CYANAMID COMPANY (US) 1977-11-08 US disclosed
US-4007210-A PROSTANOIC ACID DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1977-02-08 US disclosed
US-3970683-A 11,15-Dihydroxy-9-oxoprost-13-ynoic acid G. D. SEARLE & CO. (US) 1976-07-20 US disclosed
US-3969391-A Preparation of prostaglandin precursors G. D. SEARLE & CO. (US) 1976-07-13 US disclosed
US-3966773-A BRONCHODILATOR, HYPOTENSIVE, ANTIULCER AMERICAN CYANAMID COMPANY (US) 1976-06-29 US disclosed
US-3950406-A BRONCHODILATORS, HYPOTENSIVE, ANTIULCER AMERICAN CYANAMID COMPANY (US) 1976-04-13 US disclosed
US-3932479-A BRONCHODILATOR, HYPOTENSIVE, ANTIULCER AMERICAN CYANAMID COMPANY (US) 1976-01-13 US disclosed